Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
malathion
CAS # 121-75-5
Categories*
Household product ingredient
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Goldner WS, Sandler DP, Yu F, Shostrom V, Hoppin JA, Kamel F, LeVan TD. Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study. Journal of occupational and environmental medicine/American College of Occupational and Environmental Medicine. 2013 Oct;55(10):1171.
Ozmen G, Akay MT. 1993. The effects of malathion on some hormone levels and tissues secreting these hormones in rats. Veterinary & Human Toxicology 35(1):22-24.
Panahi P, Vosough-Ghanbari S, Pournourmohammadi S, Ostad SN, Nikfar S, Minaie B, Abdollahi M. 2006. Stimulatory effects of malathion on the key enzymes activities of insulin secretion in Langerhans islets, glutamate dehydrogenase and glucokinase. Toxicology Mechanisms & Methods 16(4):161-167.
Pournourmohammadi S, Farzami B, Ostad SN, Azizi E, Abdollahi M. 2005. Effects of malathion subchronic exposure on rat skeletal muscle glucose metabolism. Environmental Toxicology & Pharmacology 19(1):191-196.
Reuber MD. 1985. Carcinogenicity and toxicity of malathion and malaoxon. Environ Res 37(1):119-153.
Van den Berg KJ, van Raaij JAGM, Bragt PC, Notten WRF. 1991. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Arch Toxicol 65(1):15-19.
*Category References
Compendium of Pesticide Common Names (CPCN).
US Dept of Health & Human Services. Household Products Database.
US National Library of Medicine. Haz-Map.