Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

metam-sodium

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CAS # 137-42-8

Alternative Names

metam

metam natrium

sodium methyldithiocarbamate

Categories*
Antimicrobial
Pesticide ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Goldman JM, Cooper RL, Murr AS. 2007. Reproductive functions and hypothalamic catecholamines in response to the soil fumigant metam sodium: adaptations to extended exposures. Neurotoxicol Teratol 29(3):368-376.

Goldman JM, Stoker TE, Cooper RL, McElroy WK, Hein JF. 1994. Blockade of ovulation in the rat by the fungicide sodium n-methyldithiocarbamate - relationship between effects on the luteinizing hormone surge and alterations in hypothalamic catecholamines. Neurotoxicol Teratol 16(3):257-268.

Pruett SB, Barnes DB, Han YC, Munson AE. 1992. Immunotoxicological characteristics of sodium methyldithiocarbamate. Fundam Appl Toxicol 18(1):40-47.

Pruett SB, Fan RP, Zheng Q. 2006. Involvement of three mechanisms in the alteration of cytokine responses by sodium methyldithiocarbamate. Toxicol Appl Pharmacol 213(2):172-178.

Tilton F, Tanguay RL. 2008. Exposure to sodium metam during zebrafish somitogenesis results in early transcriptional indicators of the ensuing neuronal and muscular dysfunction. Toxicol Sci 106(1):103-112.

*Category References

US National Library of Medicine. Haz-Map.

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