Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
myclobutanil
CAS # 88671-89-0
Category*
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Hester SD, Nesnow S. 2008. Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide. Toxicol Appl Pharmacol 227(3):357-369.
Okubo T, Yokoyama Y, Kano K, Soya Y, Kano I. 2004. Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. Arch Environ Contam Toxicol 46(4):445-453.
Rockett JC, Narotsky MG, Thompson KE, Thillainadarajah I, Blystone CR, Goetz AK, Ren H, Best DS, Murrell RN, Nichols HP, Schmid JE, Wolf DC, Dix DJ. 2006. Effect of conazole fungicides on reproductive development in the female rat. Reprod Toxicol 22(4):647-658.
Trosken ER, Adamska M, Arand M, Zarn JA, Patten C, Volkel W, Lutz WK. 2006. Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology 228(1):24-32.
Trösken ER, Scholz K, Lutz RW, Völkel W, Zarn JA, Lutz WK. 2004. Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res 30(3):387-394.
*Category References
Compendium of Pesticide Common Names (CPCN).
US FDA. Everything Added to Food in the U.S.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.