Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
nonylphenol heptaethoxylate formulation
CAS # 9036-19-5 (Igepal CO-210; Igepal CO-720; Polyethylene glycol mono(octylphenyl) ether) / 68412-54-4 (Igepal CO-720 nonoxynol-12)
Alternative Names
Igepal CO-720
nonoxynol-12
Categories*
Household product ingredient
Personal care product/Cosmetic ingredient
Plastic/Rubber
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Kassotis CD, Klemp KC, Vu DC, Lin CH, Meng CX, Besch-Williford CL, Pinatti L, Zoeller RT, Drobnis EZ, Balise VD, and Isiguzo CJ, 2015. Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology, 156(12), pp.4458-4473.
Petit F, Le Goff P, Cravedi JP, Valotaire Y, Pakdel F. 1997. Two complementary bioassays for screening the estrogenic potency of xenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures. J Mol Endocrinol 19(3):321-335.
*Category References
Petit F, Le Goff P, Cravedi JP, Valotaire Y, Pakdel F. 1997. Two complementary bioassays for screening the estrogenic potency of xenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures. J Mol Endocrinol 19(3):321-335.
Rhodia
Waxman HA, Markey EJ, and DeGette D. 2011. Chemicals used in hydraulic fracturing. United States House of Representatives Committee on Energy and Commerce Minority Staff.