Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
nordihydroguariaretic acid
CAS # 500-38-9
Categories*
Biogenic compound
Byproduct/Intermediate/Reactant
Evidence Supporting This Chemical as an Endocrine Disruptor
Blair RM, Fang H, Branham WS, Hass BS, Dial SL, Moland CL, Tong W, Shi L, Perkins R, Sheehan DM. 2000. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol Sci 54(1):138-153.
*Category References
Arteaga S, Andrade-Cetto A, Cardenas R. 2005. Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid. J Ethnopharmacol 98(3):231-239.
Rahman S, Ansari RA, Rehman H, Parvez S, Raisuddin S. 2011. Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin. Evid Based Complement Alternat Med 2011:734785.