Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
o,p'-DDE
CAS # 3424-82-6
Alternative Names
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
2,4'-DDE
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Bitman J, Cecil HC, Harris SJ, Feil VJ. 1978. Estrogenic activity of o,p'-DDT metabolites and related compounds. J Agric Food Chem 26(1):149-151.
Kramer VJ, Giesy JP. 1999. Specific binding of hydroxylated polychlorinated biphenyl metabolites and other substances to bovine calf uterine estrogen receptor: structure-binding relationships. Sci Total Environ 233(1-3):141-161.
Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G. 2004. Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. Anal Bioanal Chem 378(3):664-669.
Soto AM, Sonnenschein C, Chung KL, Fernandez MF, Olea N, Serrano FO. 1995. The E-SCREEN assay as a tool to identify estrogens: An update on estrogenic environmental pollutants. Environ Health Perspect 103 (Suppl. 7):113-122.
*Category References
US National Library of Medicine. Hazardous Substances Data Bank. (DDT)