Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
octamethylcyclotetrasiloxane
CAS # 556-67-2
Alternative Name
D4
Categories*
Byproduct/Intermediate/Reactant
Food additives and contact material
Household product ingredient
Personal care product/Cosmetic ingredient
Pesticide ingredient
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
McKim JM Jr., Wilga PC, Breslin WJ, Plotzke KP, Gallavan RH, Meeks RG. 2001. Potential estrogenic and antiestrogenic activity of the cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) in immature rats using the uterotrophic assay. Toxicol Sci 63(1):37-46.
*Category References
US Dept of Health & Human Services. Household Products Database.
US EPA. InertFinder.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.