Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
p,p'-DDD
CAS # 72-54-8
Alternative Names
p,p'-TDE
1,1-bis(4-chlorophenyl)-2,2-dichloroethane
4,4'-DDD
Categories*
Metabolite/Degradate
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Klotz DM, Beckman BS, Hill SM, McLachlan JA, Walters MR, Arnold SF. 1996. Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays. Environ Health Perspect 104(10):1084-1089.
Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K. 2004. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect 112(5):524-531.
Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G. 2004. Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. Anal Bioanal Chem 378(3):664-669.
Van den Berg KJ, van Raaij JAGM, Bragt PC, Notten WRF. 1991. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Arch Toxicol 65(1):15-19.
*Category References
PANNA. PAN Pesticide Database.
US National Library of Medicine. Hazardous Substances Data Bank. (DDD)