Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

p,p'-DDT

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CAS # 50-29-3

Alternative Names

1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane

dichlorodiphenyltrichloroethane

4,4'-DDT

Category*
Pesticide ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Danzo BJ. 1997. Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environ Health Perspect 105(3):294-301.

Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K. 2004. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect 112(5):524-531.

Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G. 2004. Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors. Anal Bioanal Chem 378(3):664-669.

Soto AM, Sonnenschein C, Chung KL, Fernandez MF, Olea N, Serrano FO. 1995. The E-SCREEN assay as a tool to identify estrogens: An update on estrogenic environmental pollutants. Environ Health Perspect 103 (Suppl. 7):113-122.

*Category References

US National Library of Medicine. Hazardous Substances Data Bank. (DDT)

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