Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
resorcinol
CAS # 108-46-3
Alternative Names
1,3-dihydroxybenzene
1,3-benzenediol
Categories*
Household product ingredient
Industrial additive
Medical/Veterinary/Research
Personal care product/Cosmetic ingredient
Pesticide ingredient
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
Aiston S, Agius L. 1999. Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin. Diabetes 48(1):15-20.
Alanko J, Riutta A, Mucha I, Vapaatalo H, Metsa-Ketela T. 1993. Modulation of arachidonic acid metabolism by phenols: relation to positions of hydroxyl groups and peroxyl radical scavenging properties. Free Radic Biol Med 14(1):19-25.
Divi RL, Doerge DR. 1994. Mechanism-based inactivation of lactoperoxidase and thyroid peroxidase by resorcinol derivatives. Biochemistry (Mosc) 33(32):9668-9674.
Lindsay RH, Hill JB, Gaitan E, Cooksey RC, Jolley RL. 1992. Antithyroid effects of coal-derived pollutants. J Toxicol Environ Health 37(4):467-481.
Welsch F, Nemec MD, Lawrence WB. 2008. Two-generation reproductive toxicity study of resorcinol administered via drinking water to Crl:CD(SD) Rats. Int J Toxicol 27(1):43-57.
*Category References
National Pesticide Information Retrieval System.
US Dept of Health & Human Services. Household Products Database.
US EPA. InertFinder.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.