Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
styrene
CAS # 100-42-5
Categories*
Household product ingredient
Pesticide ingredient
Plastic/Rubber
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Kassotis CD, Klemp KC, Vu DC, Lin CH, Meng CX, Besch-Williford CL, Pinatti L, Zoeller RT, Drobnis EZ, Balise VD, et al. 2015 in press. Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology:en20151375.
Kassotis CD, Tillitt DE, Davis JW, Hormann AM, Nagel SC. 2014. Estrogen and androgen receptor activities of hydraulic fracturing chemicals and surface and ground water in a drilling-dense region. Endocrinology 155(3):897-907.
Mutti A, Falzoi M, Romanelli A, Franchini I. 1984. Regional alterations of brain catecholamines by styrene exposure in rabbits. Arch Toxicol 55(3):173-177.
Takao T, Nanamiya W, Nazerloo HP, Asaba K, Hashimoto K. 2000. Possible reproductive toxicity of styrene in peripubertal male mice. Endocr J 47(3):343-347.
Zaidi NF, Agrawal AK, Srivastava SP, Seth PK. 1985. Effect of gestational and neonatal styrene exposure on dopamine receptors. Neurobehavioral Toxicology & Teratology 7(1):23-28.
*Category References
Colborn T, Schultz K, Herrick L, Kwiatkowski C. 2014. An Exploratory Study of Air Quality near Natural Gas Operations. Hum Ecol Risk Assess 20(1):86-105.
McKenzie LM, Witter RZ, Newman LS, Adgate JL. 2012. Human health risk assessment of air emissions from development of unconventional natural gas resources. Sci Total Environ 424:79-87.
US Dept of Health & Human Services. Household Products Database.
US EPA. InertFinder.
US National Library of Medicine. Haz-Map.
Ziemkiewicz PF, Quaranta JD, Darnell A, Wise R. 2014. Exposure pathways related to shale gas development and procedures for reducing environmental and public risk. J Nat Gas Sci Eng 16(0):77-84.
Ziemkiewicz PF, Thomas He Y. 2015. Evolution of water chemistry during Marcellus Shale gas development: A case study in West Virginia. Chemosphere 134:224-231.