Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
tributyltin acetate
CAS # 56-36-0
Alternative Name
TBT acetate
Categories*
Food additives and contact material
Household product ingredient
Industrial additive
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Suzuki N, Tabata MJ, Kambegawa A, Srivastav AK, Shirnada A, Takeda H, Kobayashi M, Wada S, Katsumata T, Hattori A. 2006. Tributyltin inhibits osteoblastic activity and disrupts calcium metabolism through an increase in plasma calcium and calcitonin levels in teleosts. Life Sci 78(21):2533-2541.
*Category References
Abraha AB, Whalen MM. 2009. The role of p44/42 activation in tributyltin-induced inhibition of human natural killer cells: effects of MEK inhibitors. J Appl Toxicol 29(2):165-173.
Atanasov AG, Nashev LG, Tan S, Baker ME, Odermatt A. 2005. Organotins disrupt the 11[beta]-hydroxysteroid dehydrogenase type 2-dependent local inactivation of glucocorticoids. Environ Health Perspect 113(11):1600-1606.
US FDA. 2011. List of Indirect Additives Used in Food Contact Substances.
Yamada S, Fuji Y, Mikami E, Kawamura N, Hayakawa J. 1993. Small-scale survey of organotin compounds in household commodities. J AOAC Int 76(2):436-441.