Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
triclosan
CAS # 3380-34-5
Alternative Names
TCS
2'-hydroxy-2,4,4'-trichlorodiphenyl ether
2'-OH-PCDE-28
2,4,4'-trichloro-2'-hydroxydiphenyl ether
Irgasan
Categories*
Antimicrobial
Household product ingredient
Industrial additive
Medical/Veterinary/Research
Personal care product/Cosmetic ingredient
Pesticide ingredient
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kultz D, Chang DPY, Gee SJ, Hammock BD. 2008. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: Receptor-based bioassay screens. Environ Health Perspect 116(9):1203-1210.
Zorrilla LM, Gibson EK, Jeffay SC, Crofton KM, Setzer WR, Cooper RL, Stoker TE. 2009. The effects of triclosan on puberty and thyroid hormones in male Wistar rats. Toxicol Sci 107(1):56-64.
*Category References
US Dept of Health & Human Services. Household Products Database.
US EPA. 2008. Reregistration Eligibility Decision for Triclosan.