Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
trihydroxy-methoxychlor
CAS # n/a
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Gaido KW, Maness SC, McDonnell DP, Dehal SS, Kupfer D, Safe S. 2000. Interaction of methoxychlor and related compounds with estrogen receptor [alpha] and [beta], and androgen receptor: structure-activity studies. Mol Pharmacol 58(4):852-858.
*Category References
Kupfer D, Bulger WH, Theoharides AD. 1990. Metabolism of methoxychlor by hepatic P-450 monooxygenases in rat and human. 1. Characterization of a novel catechol metabolite. Chem Res Toxicol 3(1):8-16.