Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
triphenyl phosphate
CAS # 115-86-6
Alternative Names
TPP
Phosphoric acid, triphenyl ester
Categories*
Flame retardant
Industrial additive
Personal care product/Cosmetic ingredient
Pesticide ingredient
Plastic/Rubber
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Kojima H, Takeuchi S, Itoh T, Iida M, Kobayashi S, Yoshida T. 2013. In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors. Toxicology 314(1):76-83.
Liu X, Ji K, Jo A, Moon HB, Choi K. 2013. Effects of TDCPP or TPP on gene transcriptions and hormones of HPG axis, and their consequences on reproduction in adult zebrafish (Danio rerio). Aquat Toxicol 134-135:104-111.
Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. 2009. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect 117(12):1867-1872.
*Category References
Orem WH, Tatu CA, Lerch HE, Rice CA, Bartos TT, Bates AL, Tewalt S, Corum MD. 2007. Organic compounds in produced waters from coalbed natural gas wells in the Powder River Basin, Wyoming, USA. Appl Geochem 22(10):2240-2256.
US Dept of Health & Human Services. Household Products Database.
US EPA. InertFinder.
US National Library of Medicine. Haz-Map.