Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
1,3,7,8-tetrachlorodibenzo-p-dioxin
CAS # 50585-46-1
Alternative Name
1,3,7,8-TCDD
Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Evidence Supporting This Chemical as an Endocrine Disruptor
Harper N, Wang X, Liu H, Safe S. 1994. Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists. Molecular & Cellular Endocrinology 104(1):47-55.
*Category References
Mason G, Farrell K, Keys B, Piskorska-Pliszczynska J, Safe L, Safe S. 1986. Polychlorinated dibenzo-p-dioxins: Quantitative in vitro and in vivo structure-activity relationships. Toxicology 41(1):21-31.
US EPA. 2011 Apr 6. Landfill Methane Outreach Program FAQ: Public Health, Safety, and the Environment.
US National Library of Medicine. Hazardous Substances Data Bank.