Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
benz[a]anthracene
CAS # 56-55-3
Alternative Names
1,2-benzanthracene
benzo[a]anthracene
benzo[b]phenanthrene
Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Fertuck KC, Kumar S, Sikka HC, Matthews JB, Zacharewski TR. 2001. Interaction of PAH-related compounds with the alpha and beta isoforms of the estrogen receptor. Toxicol Lett 121(3):167-177.
Machala M, Vondracek J, Blaha L, Ciganek M, Neca JV. 2001. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutat Res 497(1-2):49-62.
Vinggaard AM, Hnida C, Larsen JC. 2000. Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro. Toxicology 145(2-3):173-183.
Vondracek J, Kozubík A, Machala M. 2002. Modulation of estrogen receptor-dependent reporter construct activation and G0/G1-S-phase transition by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells. Toxicol Sci 70(2):193-201.
*Category References
ATSDR. 1995. Toxicological Profile for Polycyclic Aromatic Hydrocarbons.
Colborn T, Schultz K, Herrick L, Kwiatkowski C. 2014. An Exploratory Study of Air Quality near Natural Gas Operations. Hum Ecol Risk Assess 20(1):86-105.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.
Zielinska B, Campbell D, Samburova V. 2014. Impact of emissions from natural gas production facilities on ambient air quality in the Barnett Shale area: a pilot study. J Air Waste Manag Assoc 64(12):1369-1383.