Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
naphthalene
CAS # 91-20-3
Categories*
Byproduct/Intermediate/Reactant
Household product ingredient
Pesticide ingredient
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Ahmad I, Pacheco M, Santos MA. 2003. Naphthalene-induced differential tissue damage association with circulating fish phagocyte induction. Ecotoxicol Environ Saf 54(1):7-15.
Evanson M, Van Der Kraak GJ. 2001. Stimulatory effects of selected PAHs on testosterone production in goldfish and rainbow trout and possible mechanisms of action. Comp Biochem Physiol C Toxicol Pharmacol 130(2):249-258.
Gesto M, Tintos A, Soengas JL, Miguez JM. 2006. Effects of acute and prolonged naphthalene exposure on brain monoaminergic neurotransmitters in rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology C-Toxicology and Pharmacology 144(2):173-183.
Kassotis CD, Klemp KC, Vu DC, Lin CH, Meng CX, Besch-Williford CL, Pinatti L, Zoeller RT, Drobnis EZ, Balise VD, et al. 2015 in press. Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology:en20151375.
Kassotis CD, Tillitt DE, Davis JW, Hormann AM, Nagel SC. 2014. Estrogen and androgen receptor activities of hydraulic fracturing chemicals and surface and ground water in a drilling-dense region. Endocrinology 155(3):897-907.
Pollino CA, Georgiades E, Holdway DA. 2009. Physiological changes in reproductively active rainbowfish (Melanotaenia fluviatilis) following exposure to naphthalene. Ecotoxicol Environ Saf 72(4):1265-1270.
Sarojini R, Nagabhushanam R, Fingerman M. 1995. Naphthalene-induced atresia in the ovary of the crayfish, Procambarus clarkii. Ecotoxicol Environ Saf 31(1):76-83.
*Category References
ATSDR. 2005. Toxicological Profile for Naphthalene, 1-Methylnaphthalene and 2-Methylnaphthalene.
Compendium of Pesticide Common Names (CPCN).
US Dept of Health & Human Services. Household Products Database.
US National Library of Medicine. Haz-Map.
Waxman HA, Markey EJ, and DeGette D. 2011. Chemicals used in hydraulic fracturing. United States House of Representatives Committee on Energy and Commerce Minority Staff.