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Prenatal Origins of Endocrine Disruption

Prenatal Origins of Disorders

Exposure to low-doses of endocrine disrupting chemicals rarely causes gross abnormalities that are obvious at birth. A more likely scenario is that they interfere with the programming that occurs during development, thus creating disease susceptibilities later in life. When people find themselves faced with fertility problems, breast cancer, prostate cancer, diabetes, or thyroid problems, they rarely think, “I wonder what I might have been exposed to in my mother’s womb.” Yet this may be exactly where the answer lies.

The time frame between exposure and the appearance of disease can be long and is often complicated by many intervening factors. It is only now, after four generations of humans exposed in the womb, that we can look at population level statistics and see increases in diseases and disorders that are difficult to explain through other variables.

The following is a list of human disorders that have increased in prevalence since the 1970s. There is now sufficient evidence from human epidemiological and lab animal studies to support the hypothesis that these disorders could in part be the result of prenatal exposure to endocrine disrupting chemicals.

Central Nervous System

Autism
Attention Deficit Hyperactivity Disorder Learning Disabilities
Parkinson’s Disease
Alzheimer’s Disease

Female Reproductive System

Endometriosis

Breast Cancer

Polycystic Ovary Syndrome

Male Reproductive System

Cryptorchidism (undescended testicles)
Hypospadias
Infertility/Subfertility
Testicular Cancer
Prostate Cancer

Other

Juvenile Diabetes
Obesity
Autoimmune Disorders
Asthma
Osteoporosis
Juvenile Cancer

Thyroid Disorders