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The Endocrine Disruption Exchange
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The Science of Fracking and Health

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Sapouckey, et al. (2018) Prenatal exposure to unconventional oil and gas operation chemical mixtures altered mammary gland development in adult female mice.

Kassotis, et al. (2016) Adverse reproductive and developmental health outcomes following prenatal exposure to a hydraulic fracturing chemical mixture in female C57Bl/6 mice.

Vandenberg, et al. (2012) Environmental chemicals: large effects from low doses.

Rudel, et al. (2011) Environmental exposures and mammary gland development: state of the science, public health implications, and research recommendations.

Silva, et al. (2002) Something from "nothing" - eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects.

The mammary gland is a sensitive organ: lessons learned from uog chemical mixtures

Research demonstrates that the mammary gland is particularly vulnerable to environmental chemical exposures, especially during critical windows of development. In this new webinar, Dr. Laura Vandenberg reviews the latest research on effects of endocrine disruptors on the mammary gland. She then presents results from her recently published study of mice exposed in utero to a mixture of chemicals used in unconventional oil and gas (UOG) operations. The striking effects of both high and low doses of UOG chemicals on developmentally exposed adult mammary glands are discussed.

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Photo of Dr. VandenbergLaura Vandenberg, PhD earned her BS degree from Cornell University in 2003 and her PhD from Tufts University School of Medicine in 2008. After postdoc positions at The Forsyth Institute at Harvard School of Dental Medicine and Tufts University, Dr. Vandenberg joined the faculty in the Department of Environmental Health Sciences at the University of Massachusetts Amherst in Fall 2013. Dr. Vandenberg’s laboratory research focuses on how low level exposures to environmental endocrine disruptors can induce diseases including infertility, metabolic syndrome, and breast cancer. Dr. Vandenberg is an author on more than 70 peer reviewed papers and nine book chapters. She has served on a number of US and international expert panels to assess endocrine disrupting chemicals and regularly speaks with regulatory agencies around the world.