Three layers of mesenchyme are present. The deepest layer undergoes epithelial down growth.
Duration: 3 weeks
Gusterson BA, Stein T. 2012. Human breast development. Seminars in Cell and Developmental Biology 23(5):567-573.
The promordial breast cells are clearly delineated as a discrete population.
Howard BA, Gusterson BA. 2000. Human breast development. Journal of Mammary Gland Biology and Neoplasia 5(2):119-137.
BCL-2, a molecule that prevents apoptosis, is expressed in the stromal cells adjacent to the breast bud.
Howard BA, Gusterson BA. 2000. Human breast development. Journal of Mammary Gland Biology and Neoplasia 5(2):119-137.