Hypothalamic nuclei and supraoptic tract detected.
Duration: 2 weeks
Fisher DA. 1997. Fetal thyroid function: Diagnosis and management of fetal thyroid disorders. Clinical Obstetrics & Gynecology 40(1):16-31.
Arginine vasopressin (AVP) detected. Lactrotropes (which produce prolactin) present.
Kaplan SL, Grumbach MM, Aubert ML. 1976. The ontogenesis of pituitary hormones and hypothalamic factors in the human fetus: maturation of central nervous system regulation of anterior pituitary function. Recent Prog Horm Res 32:161-243.
Plasma cortisol found in low concentrations.
Kaplan SL, Grumbach MM, Aubert ML. 1976. The ontogenesis of pituitary hormones and hypothalamic factors in the human fetus: maturation of central nervous system regulation of anterior pituitary function. Recent Prog Horm Res 32:161-243.
Follicle-stimulating hormone and luteinizing hormone detected.
Kaplan SL, Grumbach MM, Aubert ML. 1976. The ontogenesis of pituitary hormones and hypothalamic factors in the human fetus: maturation of central nervous system regulation of anterior pituitary function. Recent Prog Horm Res 32:161-243.
Endogenous fetal thyroid hormone produced, which influences development.
Duration: 26 weeks
Sadler TW. 2000. Susceptible periods during embryogenesis of the heart and endocrine glands. Environ Health Perspect 108 (suppl 3):555-561.
Gonadotropes for LH present.
Sadler TW. 2000. Susceptible periods during embryogenesis of the heart and endocrine glands. Environ Health Perspect 108 (suppl 3):555-561.
Differentiation of the chromaffin tissue in the medulla begins and continues until 12-18 months after birth.
Duration: 26 weeks
Sadler TW. 2000. Susceptible periods during embryogenesis of the heart and endocrine glands. Environ Health Perspect 108 (suppl 3):555-561.
First signs of vascularization.
Duration: 1 week
Hahn von Dorsche H, Falkmer S. 2000. Ontogenesis of human islets of Langerhans. Review of light and electron microscopic data, immunohistochemical and functional data on fetal development of the endocrine pancreas. Journal of Evolutionary Biochemistry and Physiology 36(6):701-718.
Limbs: Primary ossification centers are present in all long bones of the limbs.
Sadler TW. 2004. Langman’s Medical Embryology. Ninth Edition. Maryland: Lippincott Williams & Wilkins.
Prolactin detected.
Kaplan SL, Grumbach MM, Aubert ML. 1976. The ontogenesis of pituitary hormones and hypothalamic factors in the human fetus: maturation of central nervous system regulation of anterior pituitary function. Recent Prog Horm Res 32:161-243.