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2 results for: Bisphenol A, Central Nervous System — WEEK 19

The weeks shown in color represent the start and end points of chemical exposure for each study.
Study Results Study Details References

Results for Bisphenol A

Decreased paw-jerk frequency 30-60 minutes after pain (formalin) injection

Subjects: SD rats

Chemical: Bisphenol A

Low doses tested: 40 μg/kg bw/d

Route of administration: dissolved in peanut oil and fed to the dam with a pipette

Exposure duration: post-natal day 0 – post-natal day 21 (comparable to human prenatal development from approximately day 1 of week 19 to beyond birth)

Age of measurement: 22 weeks of age

 Reference [PubMed Link]
Aloisi AM, Della Seta D, Rendo C, Ceccarelli I, Scaramuzzino A, Farabollini F. 2002. Exposure to the estrogenic pollutant bisphenol A affects pain behavior induced by subcutaneous formalin injection in male and female rats. Brain Res 937(1-2):1-7.
Study Results Study Details References

Results for Bisphenol A

Increased sexual motivation and receptive behavior in females; decreased sexual performance in males

Subjects: SD rats

Chemical: Bisphenol A

Low doses tested: 40 μg/kg bw/d

Route of administration: dissolved in arachis oil and fed with a pipette

Exposure duration: gestational day 23 – post-natal day 19 (comparable to human prenatal development from approximately day 1 of week 19 to beyond birth)

Age of measurement: 100 days of age

 Reference [PubMed Link]
Farabollini F, Porrini S, Della Seta D, Bianchi F, Dessi-Fulgheri F. 2002. Effects of perinatal exposure to bisphenol A on sociosexual behavior of female and male rats. Environ Health Perspect 110 (suppl 3):409-413.