The weeks shown in color represent the start and end points of chemical exposure for each study.
Study Results | Study Details | References |
Results for Phthalates (DBP)Decreased frequency of grooming at 0.01 mg/kg |
Subjects: Sprague-Dawley rats Chemical: Phthalates (DBP) Low doses tested: 0.01 or 1.0 mg/kg bw/d Route of administration: dissolved in sesame oil and delivered in feed Exposure duration: gestational day 8 – gestational day 22 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 18) Age of measurement: birth through 4 weeks of age |
Reference [PubMed Link] Hoshi H, Ohtsuka T. 2009. Adult Rats Exposed to Low-Doses of Di-n-Butyl Phthalate During Gestation Exhibit Decreased Grooming Behavior. Bull Environ Contam Toxicol 83(1):62-66. |