References popup

The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Chlorpyrifos

Delayed vaginal opening at 5 mg/kg

Subjects: Sprague-Dawley rats

Chemical: Chlorpyrifos

Low doses tested: 0.3, 1.0, or 5.0 mg/kg bw/d

Route of administration: dissolved in corn oil and delivered through gavage

Exposure duration: gestational day 6 – post-natal day 10 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 31)

Age of measurement: birth through adulthood

Reference [PubMed Link]
Maurissen JPJ, Hoberman AM, Garman RH, Hanley TR. 2000. Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos. Toxicol Sci 57(2):250-263.