The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for Dioxin (TCDD)Decreased percentage with testis descent at 16 days of age at higher dose only
Subjects: Wistar rats
Chemical: Dioxin (TCDD)
Low doses tested: 0.3 or 1.0 μg/kg bw
Other doses tested: Initial dose was followed by weekly maintenance doses (at 40 percent)
Route of administration: injected subcutaneously
Exposure duration: gestational day 19 – adulthood (comparable to human prenatal development from approximately day 1 of week 10 to beyond birth)
Age of measurement: birth through adulthood
|Reference [PubMed Link]
Thiel R, Koch E, Ulbrich B, Chahoud I. 1994. Peri- and postnatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin - effects on physiological development, reflexes, locomotor activity and learning behaviour in Wistar rats. Arch Toxicol 69(2):79-86.