The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for Dioxin (TCDD)Decreased AhR protein concentration (but not ARNT) in the ventral and dorsolateral prostate
Subjects: Holtzman rats
Chemical: Dioxin (TCDD)
Low doses tested: 5.0 μg/kg bw
Route of administration: injected intraperitoneally
Exposure duration: post-natal day 6 – single dose (comparable to human prenatal development from approximately day 1 of week 26 to day 1 of week 27)
Age of measurement: 6 days of age
|Reference [PubMed Link]
Sommer RJ, Sojka KM, Pollenz RS, Cooke PS, Peterson RE. 1999. Ah receptor and arnt protein and mRNA concentrations in rat prostate: Effects of stage of development and 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Toxicology & Applied Pharmacology 155(2):177-189.