The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for Dioxin (TCDD)Decreased relative thymus weight at 0.3 μg/kg
Subjects: Wistar rats
Chemical: Dioxin (TCDD)
Low doses tested: 0.3 or 3.0 μg/kg bw
Route of administration: injected subcutaneously
Exposure duration: gestational day 19 – single dose (comparable to human prenatal development from approximately day 1 of week 10 to day 1 of week 11)
Age of measurement: 77 days of age
Korte M, Stahlmann R, Thiel R, Nagao T, Chahoud I, Vanloveren H, Vos JG, Neubert D. 1991. Resistance to trichinella-spiralis infection, induction of hepatic monooxygenases, and concentrations in thymus and liver in rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemosphere 23(11-12):1845-1854.