References popup

The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Dioxin (TCDD)

Decreased relative thymus weight at 0.3 μg/kg

Subjects: Wistar rats

Chemical: Dioxin (TCDD)

Low doses tested: 0.3 or 3.0 μg/kg bw

Route of administration: injected subcutaneously

Exposure duration: gestational day 19 – single dose (comparable to human prenatal development from approximately day 1 of week 10 to day 1 of week 11)

Age of measurement: 77 days of age

Korte M, Stahlmann R, Thiel R, Nagao T, Chahoud I, Vanloveren H, Vos JG, Neubert D. 1991. Resistance to trichinella-spiralis infection, induction of hepatic monooxygenases, and concentrations in thymus and liver in rats after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemosphere 23(11-12):1845-1854.