Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
4,4'-dihydroxystilbene
CAS # 659-22-3
Category*
Medical/Veterinary/Research
Evidence Supporting This Chemical as an Endocrine Disruptor
Blair RM, Fang H, Branham WS, Hass BS, Dial SL, Moland CL, Tong W, Shi L, Perkins R, Sheehan DM. 2000. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol Sci 54(1):138-153.
*Category References
Lappano R, Rosano C, Madeo A, Albanito L, Plastina P, Gabriele B, Forti L, Stivala LA, Iacopetta D, Dolce V, Ando S, Pezzi V, Maggiolini M. 2009. Structure-activity relationships of resveratrol and derivatives in breast cancer cells. Mol Nutr Food Res 53(7):845-858.
Sanoh S, Kitamura S, Sugihara K, Ohta S. 2002. Cytochrome P450 1A1/2 mediated metabolism of trans-stilbene in rats and humans. Biol Pharm Bull 25(3):397-400.