Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

benzo[a]pyrene

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CAS # 50-32-8

Alternative Names

benz[a]pyrene

benzo(d,e,f)chrysene

Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Unconventional Oil and Gas

Evidence Supporting This Chemical as an Endocrine Disruptor

Machala M, Vondracek J, Blaha L, Ciganek M, Neca JV. 2001. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutat Res 497(1-2):49-62.

Thomas P. 1990. Teleost model for studying the effects of chemicals on female reproductive endocrine function. J Exp Zool Suppl 4:126-128.

Vinggaard AM, Hnida C, Larsen JC. 2000. Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro. Toxicology 145(2-3):173-183; DOI: 10.1016/S0300-483X(00)00143-8.

*Category References

ATSDR. 1995. Toxicological Profile for Polycyclic Aromatic Hydrocarbons. [http://www.atsdr.cdc.gov/toxprofiles/tp69.pdf]

Colborn T, Schultz K, Herrick L, Kwiatkowski C. 2014. An Exploratory Study of Air Quality near Natural Gas Operations. Hum Ecol Risk Assess 20(1):86-105; DOI:110.1080/10807039.10802012.10749447.

Paulik LB, Donald CE, Smith BW, Tidwell LG, Hobbie KA, Kincl L, Haynes EN, and Anderson KA, 2016. Emissions of Polycyclic Aromatic Hydrocarbons from Natural Gas Extraction into Air. Environ Sci Technol, 50(14), pp.7921-7929.

US National Library of Medicine. Haz-Map. [http://hazmap.nlm.nih.gov/index.php].

US National Library of Medicine. Hazardous Substances Data Bank. [http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB].

Zielinska B, Campbell D, Samburova V. 2014. Impact of emissions from natural gas production facilities on ambient air quality in the Barnett Shale area: a pilot study. J Air Waste Manag Assoc 64(12):1369-1383.

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