Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

chrysophanol

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CAS # 481-74-3

Categories*
Biogenic compound
Medical/Veterinary/Research
Metabolite/Degradate
Personal care product/Cosmetic ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Matsuda H, Shimoda H, Morikawa T, Yoshikawa M. 2001. Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorganic & Medicinal Chemistry Letters 11(14):1839-1842.

*Category References

Kim DH. 2000. Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions. Biol Pharm Bull 23:830-833.

Matsuda H, Shimoda H, Morikawa T, Yoshikawa M. 2001. Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorg Med Chem Lett 11(14):1839-1842.

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