Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

2,2',4,6,6'-pentachlorobiphenyl

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CAS # 56558-16-8

Alternative Name

PCB-104

Category*
Industrial additive

Evidence Supporting This Chemical as an Endocrine Disruptor

Fielden MR, Chen I, Chittim B, Safe SH, Zacharewski TR. 1997. Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155). Environ Health Perspect 105(11):1238-1248.

*Category References

CDPH. 1988. Polychlorinated Biphenyls (PCBs). Fact Sheet. [http://www.cdph.ca.gov/programs/hesis/Documents/pcbs.pdf]

UNEP. 1999. Guidlines for the Identification of PCBs and Materials Containing PCB [http://www.chem.unep.ch/Publications/pdf/GuidIdPCB.pdf]

US EPA. 2012. Aroclor and other PCB mixtures. [http://www.epa.gov/osw//hazard/tsd/pcbs/pubs/aroclor.htm].

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