Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

nordihydroguariaretic acid


CAS # 500-38-9

Biogenic compound

Evidence Supporting This Chemical as an Endocrine Disruptor

Blair RM, Fang H, Branham WS, Hass BS, Dial SL, Moland CL, Tong W, Shi L, Perkins R, Sheehan DM. 2000. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol Sci 54(1):138-153.

*Category References

Arteaga S, Andrade-Cetto A, Cardenas R. 2005. Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid. J Ethnopharmacol 98:231-223

Rahman S, Ansari RA, Rehman H, Parvez S, Raisuddin S. 2011. Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin. Evidence-Based Complementary and Alternative Medicine :Article ID 734785, 10 pages, doi:10.1093/ecam/nep076. [http://www.hindawi.com/journals/ecam/2011/734785/]