Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

1,3,7,8-tetrachlorodibenzo-p-dioxin

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CAS # 50585-46-1

Alternative Name

1,3,7,8-TCDD

Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research

Evidence Supporting This Chemical as an Endocrine Disruptor

Harper N, Wang X, Liu H, Safe S. 1994. Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists. Molecular & Cellular Endocrinology 104(1):47-55.

*Category References

Mason G, Farrell K, Keys B, Piskorska-Pliszczynska J, Safe L, Safe S. 1986. Polychlorinated dibenzo-p-dioxins: Quantitative in vitro and in vivo structure-activity relationships. Toxicology 41(1):21-31.

US EPA. 2011 Apr 6. Landfill Methane Outreach Program FAQ: Public Health, Safety, and the Environment. [http://www.epa.gov/lmop/faq/public.html].

US National Library of Medicine. Hazardous Substances Data Bank. [http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB].

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