Adverse reproductive and developmental health outcomes following prenatal exposure to a hydraulic fracturing chemical mixture in female C57BI/6 mice
On September 15th, 2016, Dr. Susan Nagel discussed her recent paper. Building on previous research, Dr. Nagel will present these new findings on the effects of exposing female mice in utero to a mixture of 23 chemicals commonly used in unconventional oil and gas operations via their mother’s drinking water. Effects included suppressed hormones, increased body weights, altered organ weights, and other adverse health outcomes. Effects were shown at several doses, including doses equivalent to concentrations reported in drinking water sources. Implications for humans and animals exposed to these chemicals will be discussed.
Susan Nagel, PhD, is an Associate Professor of Obstetrics, Gynecology, and Women’s Health at the University of Missouri School of Medicine. She specializes in the role of natural and synthetic hormones in development, reproduction, and disease. She has published research on hormone receptor activities of hydraulic fracturing chemicals and surface and ground water in areas heavily impacted by natural gas development.