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Per- and polyfluoroalkyl substances added to
the TEDX list of potential endocrine disruptors

Chemicals designed to repel oil and water, known as PFAS (per- and polyfluoroalkyl substances), have been used widely in everything from food wrappers, cosmetics, and textiles, to firefighting foams. As a result, they have been detected into our food, water and our bodies.

Maternal exposure to some PFAS has been linked to altered thyroid hormone levels in maternal and umbilical cord blood, a finding that is especially concerning because thyroid hormones are important in early brain development. PFAS have also been shown to activate receptors that influence hepatic lipid metabolism and to disrupt hormone synthesis.

In our latest investigation we evaluated 11 candidates and added 10 PFAS not previously on the TEDX List of Potential Endocrine Disruptors. We also confirmed additional references supporting the endocrine disrupting properties of 13 already listed chemicals (including PFOA and PFBS).

PFAS do not break down completely in the environment so exposure of humans and wildlife can occur continuously as they are transported through air, water, and soil. Currently, California, Washington, and other states are developing policies that would limit PFAS in food contact materials and address ground and drinking water contamination. Further, the US EPA just announced a new cross-agency effort to address PFAS exposure and health effects.

Is there a chemical you think should be on the TEDX List? Suggest an addition and we’ll investigate.

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TEDX is a nonprofit scientific research institute. We evaluate and interpret scientific evidence on the effects of common chemicals, known as endocrine disruptors, in order to prevent harm to human and animal health.